Mapping novel genetic loci associated with female liver weight variations using Collaborative Cross mice.

Hanifa J Abu-Toamih AtamniMaya BotzmanRichard MottIrit Gat-ViksFuad A Iraqi

Published in: Animal models and experimental medicine (2018)

To our knowledge, this report presents, for the first time, the utilization of the CC for mapping QTL associated with baseline liver weight in mice. Our findings demonstrate that liver weight is a complex trait controlled by multiple genetic factors that differ significantly between sexes.

Keyphrases

genome wide
body mass index
weight loss
physical activity
weight gain
high resolution
high density
high fat diet induced
dna methylation
copy number
body weight
type diabetes
gene expression
adipose tissue
genome wide association