Characterization of canine epidermal organoid cultures by immunohistochemical analysis and quantitative PCR.
Dominique J WienerIsabelle C StuderMagdalena A T BrunnerAndreas HermannSimona VincentiMeng ZhangKátia Regina GrochMonika M WellePublished in: Veterinary dermatology (2020)
Organoids cultured in expansion medium have an equivalent structure to the interfollicular epidermis and express key marker proteins in similar proportions. Epidermal organoids are therefore a promising in vitro model to study epidermal structure, function and dysfunction.