Beneficial Effects of Oral Carbon Monoxide on Doxorubicin-Induced Cardiotoxicity.

Rodrigo W Alves de Souza Vanessa VoltarelliDavid GalloSidharth ShankarMichael S TiftMark YoungEdward GompertsAndrew GompertsLeo Edmond Otterbein

Published in: Journal of the American Heart Association (2024)

These findings strongly support using HBI-002 as a cardioprotective agent that maintains the therapeutic benefits of doxorubicin cancer treatment while mitigating cardiac damage.

Keyphrases

drug delivery
cancer therapy
diabetic rats
high glucose
oxidative stress
left ventricular