Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif function.

Belete A DesimmieJessica L SmithHiroshi MatsuoWei-Shau HuVinay K Pathak

Published in: Retrovirology (2017)

Our results provide detailed insight into the Vif-CBFβ interactions that are critical for Vif function and may contribute to the rational design of HIV-1 inhibitors that block Vif-mediated degradation of A3 proteins.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
hiv testing
human immunodeficiency virus
hepatitis c virus
hiv aids
men who have sex with men
south africa