Phenotypic integration mediated by hormones: associations among digit ratios, body size and testosterone during tadpole development.
Leandro LofeuRenata BrandtTiana KohlsdorfPublished in: BMC evolutionary biology (2017)
We propose a model where evolution of sexual dimorphism in 2D:4D first originates from the advent, in a given digit, of increased tissue sensitivity to steroids. Phenotypic integration with other sexually dimorphic traits would then occur through multi-trait hormonal effects during development. Such process of phenotypic integration seems fitness-independent in its origin and might explain several cases of steroid-mediated integration among sexually dimorphic traits.