C9orf72 expansions are the most common cause of genetic frontotemporal dementia in a Southeast Asian cohort.

Yi Jayne TanAlisa C W YongJia Nee FooMichelle M LianWeng Khong LimJacqueline DominguezZhi Hui FongKaavya NarasimhaluHui Jin ChiewKok Pin NgSimon K S TingNagaendran KandiahAdeline S L Ng

Published in: Annals of clinical and translational neurology (2023)

In our cohort, genetic mutations are present in one-quarter of FTD-spectrum cases, and up to half of those with family history. Our findings highlight the importance of wider implementation of genetic testing in FTD patients from Southeast Asia.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
genome wide
chronic kidney disease
primary care
healthcare
peritoneal dialysis
copy number