A simple in silico strategy identifies candidate biomarkers for the diagnosis of liver fibrosis in morbidly obese subjects.
Pablo José GiraudiSabrina E GambaroSofia Ornelas ArroyoCarla M ChackeleviciusMichela GiuricinMarta SilvestriDaniele MacorLory S CrocéDeborah BonazzaGiorgio SoardoNicolò de ManziniFabrizio ZanconatiClaudio TiribelliSilvia PalmisanoNatalia RossoPublished in: Liver international : official journal of the International Association for the Study of the Liver (2017)
Our study supports the potential utility of IGF2 and EGFR as non-invasive diagnostic biomarkers for liver fibrosis in morbidly obese subjects.
Keyphrases
- liver fibrosis
- obese patients
- bariatric surgery
- weight loss
- adipose tissue
- metabolic syndrome
- small cell lung cancer
- type diabetes
- epidermal growth factor receptor
- genome wide
- gene expression
- molecular docking
- dna methylation
- climate change
- binding protein
- cell proliferation
- molecular dynamics simulations
- signaling pathway