Tract-specific damage at spinal cord level in pure hereditary spastic paraplegia type 4: a diffusion tensor imaging study.
Francisco J Navas-SánchezLuis Marcos-VidalDaniel Martín de BlasAlberto Fernández-PenaYasser Alemán-GómezJuan A Guzmán-de-VilloriaJulia RomeroIrene CatalinaLaura LilloJosé L Muñoz-BlancoAndrés Ordoñez-UgaldeBeatriz QuintánsMaría-Jesús SobridoSusanna CarmonaFrancisco GrandasManuel DescoPublished in: Journal of neurology (2022)
Our results in SPG4 indicate tract-specific axonal damage at the level of the cervical and thoracic spinal cord. This finding is correlated with the degree of motor disability.