Huaier-induced suppression of cancer-associated fibroblasts confers immunotherapeutic sensitivity in triple-negative breast cancer.

Chen LiXiaolong WangLuyao XingTong ChenWenhao LiXin LiYifei WangChao YangQifeng Yang

Published in: Phytomedicine : international journal of phytotherapy and phytopharmacology (2024)

Our findings demonstrate that Huaier regulates cancer immunity in TNBC by suppressing the transition of CAFs to myoCAFs and emphasize the crucial role of Huaier as an effective adjuvant agent in immunotherapy.

Keyphrases

papillary thyroid
high glucose
early stage
diabetic rats
squamous cell
extracellular matrix
drug induced
squamous cell carcinoma
oxidative stress
childhood cancer