Severe adverse events during second-line tuberculosis treatment in the context of high HIV Co-infection in South Africa: a retrospective cohort study.

Kathryn SchnippelRebecca H BerhanuAndrew BlackCynthia FirnhaberNorah MaitisaDenise EvansEdina Sinanovic

Published in: BMC infectious diseases (2016)

Severe AE are common during the first 6 months of RR TB treatment and HIV-positive patients newly initiating ART have the highest subdistribution hazard ratio for severe AE, accounting for the competing risks of death and loss from treatment.

Keyphrases

hiv positive
south africa
antiretroviral therapy
men who have sex with men
end stage renal disease
early onset
human immunodeficiency virus
hiv aids
chronic kidney disease
emergency department
hiv testing
combination therapy
patient reported outcomes