Intraosseous injections of platelet rich plasma for knee bone marrow lesions treatment: one year follow-up.
A LychaginMarina M LipinaA GarkaviO IslaiehP TimashevK AshmoreE KonPublished in: International orthopaedics (2020)
In our opinion, first COMP increasing can be caused by injection of platelet rich plasma. It is not adequate to interpret this growth in COMP levels as increased osteochondral degeneration. One year follow-up period showed good quality of life improvement, significant pain reduction, and essential MRI changes. The long-term observation of these cohort of patients combined with an analysis of MRI images is still ongoing.
Keyphrases
- platelet rich plasma
- bone marrow
- end stage renal disease
- magnetic resonance imaging
- contrast enhanced
- ejection fraction
- chronic kidney disease
- chronic pain
- mesenchymal stem cells
- newly diagnosed
- deep learning
- prognostic factors
- total knee arthroplasty
- peritoneal dialysis
- pain management
- convolutional neural network
- computed tomography
- magnetic resonance
- knee osteoarthritis
- optical coherence tomography
- neuropathic pain
- ultrasound guided
- spinal cord
- combination therapy