Metabolomic Association and Risk Prediction With Heart Failure in Older Adults.
Guning LiuNgoc Quynh H NguyenKari E WongSunil K AgarwalEric BoerwinklePatricia P ChangBrian Lee ClaggettLaura R LoehrJianzhong MaKunihiro MatsushitaCarlos J RodriguezJoseph S RossiStuart D RussellR Brandon StaceyAmil M ShahBing YuPublished in: Circulation. Heart failure (2024)
Novel metabolites associated with HF risk were identified, elucidating disease pathways, specifically HFpEF. An MRS was associated with HF risk and improved 5-year risk prediction in older adults, which may assist at at-risk population identification.