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Physiologically Based Pharmacokinetic Modeling to Simulate CYP3A4-Mediated Drug-Drug Interactions for Pyrotinib.

Liang NiLiang ZhengYueyue LiuWenwen XuYingjie ZhaoLing WangQian ZhangWei HuXijing Chen
Published in: Advances in therapy (2023)
PBPK modeling provides valuable information to avoid irrational medication when receiving pyrotinib chemotherapy.
Keyphrases
  • adverse drug
  • healthcare
  • locally advanced
  • emergency department
  • squamous cell carcinoma
  • rectal cancer