Severe progressive scarring pembrolizumab-induced lichen planopilaris in a patient with metastatic melanoma.

Aarthy K UthayakumarEmily RuddMariana NoyJustin WeirJames LarkinLouise Fearfield
Published in: The Australasian journal of dermatology (2021)
Lichenoid reactions are one of the many cutaneous immune-related adverse events seen with the use of immune checkpoint inhibitors, particularly anti-PD1 inhibitors. We present a rare care of severe lichen planopilaris secondary to pembrolizumab, with progression even after cessation of immunotherapy. It is important to recognise the significant long-term impact of these cutaneous adverse effects on patient's quality of life.