The prognostic significance of lymphovascular tumor invasion in localized high-grade osteosarcoma: Outcomes of a single institution over 10 years.
Charles A GushoIra MillerBishir ClaytonMatthew W ColmanSteven GitelisAlan T BlankPublished in: Journal of surgical oncology (2021)
The presence of LVI in the setting of high-grade, localized osteosarcoma is associated with greater rates of mortality and appears to portend a dismal prognosis.