Implications of the variation in biological 18 O natural abundance in body water to inform use of Bayesian methods for modelling total energy expenditure when using doubly labelled water.
Priya A SinghElise R OrfordKevin DonkersLeslie J C BluckMichelle C VenablesPublished in: Rapid communications in mass spectrometry : RCM (2018)
Our findings demonstrate that using a reduced natural variation in 18 O as calculated from a population does not impact significantly on the calculation of TEE in our model. It may therefore be more conservative to allow a larger variance to account for individual extremes.