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Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes: A Randomized, Single-Blinded, Placebo-Controlled Study.

Preeshila BeharyGeorge TharakanKleopatra AlexiadouNicholas JohnsonNicolai J Wewer AlbrechtsenJulia KenkreJoyceline CuencoDavid HopeOluwaseun AnyiamSirazum ChoudhuryHaya AlessimiiAnkur PoddarJames MinnionChedie DoyleGary FrostCarel Le RouxSanjay PurkayasthaKrishna MoorthyWaljit Singh DhilloJens Juul HolstAhmed R AhmedA Toby PrevostStephen R BloomTricia Mei-Mei Tan
Published in: Diabetes care (2019)
GOP infusion improves glycemia and reduces body weight. It achieves superior glucose tolerance and reduced glucose variability compared with RYGB and VLCD. GOP is a viable alternative for the treatment of diabetes with favorable effects on body weight.
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