Impact of Letermovir Primary Cytomegalovirus Prophylaxis on 1-Year Mortality After Allogeneic Hematopoietic Cell Transplantation: A Retrospective Cohort Study.
Yiqi SuAnat SternEleni KarantoniTamara NawarGyuri HanPhaedon ZavrasHenry DumkeChristina ChoRoni TamariBrian ShafferSergio GiraltAnn JakubowskiMiguel Angel PeralesGenovefa PapanicolaouPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
At 1 year post-HCT, LET was associated with closing the mortality disparity between R-D- and R+. Among all R+, LET was associated with decreased mortality, driven by 79% reduced incidence of death in T-cell depleted HCT.