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Methodological Quality of Pulmonary Arterial Hypertension Treatment Evidence-Based Guidelines: A Systematic Review Using the AGREE II and AGREE REX Tools.

Ana Paula Oliveira VilelaFlávia DeffertRosa Camila LucchettaYara Maria da Silva PiresFelipe Fernando MainkaFernanda Stumpf ToninRoberto Pontarolo
Published in: Cardiovascular drugs and therapy (2024)
Methodological weaknesses are common among guidelines addressing PAH treatment, especially regarding scientific rigor, stakeholders' values and preferences, and facilitators and barriers to implementability. Particular attention should be given to developing future guidelines.
Keyphrases
  • pulmonary arterial hypertension
  • clinical practice
  • combination therapy
  • quality improvement