30 years of dengue fatal cases in Brazil: a laboratorial-based investigation of 1047 cases.
Priscila Conrado Guerra NunesAna Maria Bispo de FilippisMonique Queiroz da Rocha LimaNieli Rodrigues da Costa FariaFernanda de Bruycker-NogueiraJaqueline Bastos SantosManoela HeringerThaís Chouin-CarneiroDinair Couto-LimaBianca de Santis GonçalvesSimone Alves SampaioEliane Saraiva Machado de AraújoJuan Camilo Sánchez-ArcilaFlávia Barreto Dos SantosRita Maria Ribeiro NogueiraPublished in: BMC infectious diseases (2018)
Dengue is a multifactorial disease and, factors such as viral strain/serotype, occurrence of secondary infections and co-morbidities may lead to a severe outcome. However, the high dengue incidence and transmission during epidemics, such as those observed in Brazil may overwhelm and collapse the public health services, potentially impacting on increased disease severity and mortality.