Adherence patterns in antiseizure medications influencing risk of sudden unexplained death in epilepsy: A data linkage study using dispensed prescriptions.
Michael TanSamuel S AllemannXiwen Simon QinWendyl J D'SouzaPublished in: Epilepsia (2023)
ASM nonadherence was observed in half of outpatients with epilepsy. A declining pattern of adherence, observed in a quarter of patients, was associated with more than eight times increased risk of SUDEP. Any ongoing medication interventions must include strategies to maintain and improve ASM adherence if we are to reduce the risk of SUDEP.
Keyphrases
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- ejection fraction
- healthcare
- peritoneal dialysis
- prognostic factors
- glycemic control
- emergency department
- electronic health record
- metabolic syndrome
- patient reported outcomes
- big data
- machine learning
- skeletal muscle
- deep learning
- insulin resistance
- hiv testing