Imaging glioma biology: spatial comparison of amino acid PET, amide proton transfer, and perfusion-weighted MRI in newly diagnosed gliomas.
S SchönJ CabelloF Liesche-StarneckerM Molina-RomeroP EichingerM MetzI KarimovC PreibischJ KeuppA HockB MeyerW WeberC ZimmerT PykaI YakushevJ GemptBenedikt WiestlerPublished in: European journal of nuclear medicine and molecular imaging (2020)
We found a relevant spatial overlap in glioblastomas between hotspots of APTw and FET both in contrast-enhancing and FLAIR-hyperintense tumor. As suggested by earlier studies, APTw was lower in lower-grade gliomas compared with glioblastomas. APTw meaningfully contributes to biological imaging of gliomas.