Treatment of pediatric high-grade central nervous system tumors with high-dose methotrexate in combination with multiagent chemotherapy: A single-institution experience.

Joshua D BernstockElizabeth AlvaJoshua L CohenMina LobbousGustavo ChagoyaGalal A ElsayedBrent A OrrCurtis RozzelleBrandon RocqueJeffrey BlountJames M JohnstonRong LiJohn B FiveashGirish DhallAlyssa T ReddyGregory K Friedman

Published in: Pediatric blood & cancer (2019)

DIMAC with HDMTX without HDCSCR may be an effective treatment option for selected patients with embryonal or high-grade CNS tumors.

Keyphrases

high grade
high dose
low grade
radiation therapy
rectal cancer