Superoxide free radical spin-lattice relaxivity: A quench-assisted MR study.

Martin J MacKinnon Bruce A Berkowitz Yen-Yu Ian Shih

Published in: Magnetic resonance in medicine (2021)

Our first-in-kind measurement of superoxide free radical r1 suggests a detection sensitivity of QUEST MRI on the order of tens of μM, within the reported level of free radical production during oxidative stress in vivo. Similar studies for other common free radicals are needed.

Keyphrases

oxidative stress
contrast enhanced
magnetic resonance imaging
hydrogen peroxide
dna damage
magnetic resonance
computed tomography
room temperature
signaling pathway
endoplasmic reticulum stress
induced apoptosis
molecular dynamics
ionic liquid
label free