Mobile mural thrombus and spontaneous echo contrast in ascending aorta after postoperative adjuvant cisplatin-based chemotherapy.
Yutaka AoyamaKenji HaradaYasuhiro YokoyamaYusuke IshiyamaTakahiro KomoriMasahisa ShimpoKazuomi KarioPublished in: Echocardiography (Mount Kisco, N.Y.) (2020)
A 70-year-old asymptomatic male who had undergone a right nephrectomy for renal pelvic cancer was referred to us with a thrombus in the ascending aorta detected by contrast-enhanced computed tomography after chemotherapy with gemcitabine/cisplatin. Transesophageal echocardiography revealed a 4-cm mobile mural thrombus in the ascending aorta. An emergency thoracotomy for planned aortic root replacement was performed, but the intraoperative epi-aortic ultrasound indicated that the thrombus had disappeared, and it showed prominent spontaneous-echo contrast (SEC) in the ascending aorta. We speculate that vascular endothelium damage due to the cisplatin-based chemotherapy induced the thrombus and SEC in the ascending aorta.
Keyphrases
- pulmonary artery
- contrast enhanced
- aortic dissection
- computed tomography
- pulmonary hypertension
- magnetic resonance imaging
- diffusion weighted
- magnetic resonance
- coronary artery
- aortic valve
- pulmonary arterial hypertension
- chemotherapy induced
- diffusion weighted imaging
- positron emission tomography
- patients undergoing
- locally advanced
- early stage
- public health
- emergency department
- oxidative stress
- papillary thyroid
- aortic valve replacement
- transcatheter aortic valve replacement
- rectal cancer
- dual energy
- left ventricular
- heart failure
- aortic stenosis
- squamous cell carcinoma
- image quality
- single cell
- young adults
- robot assisted
- atrial fibrillation