Childhood aplastic anaemia with paroxysmal nocturnal haemoglobinuria clones: A retrospective single-centre study in South Africa.

Candice Laverne Hendricks Ashen Naidoo Rajendra Thejpal Nadine Rapiti Beverley Neethling Yasmin Goga Suvarna Buldeo

Published in: African journal of laboratory medicine (2022)

More than half of children with AA had a PNH clone. The size of the clone did not impact clinical severity; however, IST use may positively impact prognosis. We recommend early initiation of IST in patients with AA to avoid delays associated with human leukocyte antigen typing.

Keyphrases

south africa
endothelial cells
young adults
blood pressure
obstructive sleep apnea
hiv positive
peripheral blood
sleep apnea
sleep quality