Improving Risk Stratification for Pediatric Patients with Rhabdomyosarcoma by Molecular Detection of Disseminated Disease.
Nathalie S M LakTimon L VoormannsLily Zappeij-KannegieterLieke M J van ZogchelMarta FioccoMax M van NoeselJohannes H M MerksC Ellen van der SchootGodelieve A M TytgatJanine StutterheimPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
This study shows a strong association between PCR-based detection of disseminated disease at diagnosis with clinical outcome in pediatric patients with rhabdomyosarcoma, also compared with conventional risk stratification. This warrants further validation in prospective trials as additional technique for risk stratification.
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