Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF3S-Containing Isoxazolidines.
Alejandra Riesco-DomínguezJeroen van de WielTrevor A HamlinBas van BeekStephen D LindellDaniel Blanco-AniaFriedrich Matthias BickelhauptFloris P J T RutjesPublished in: The Journal of organic chemistry (2018)
Trifluoromethyl vinyl sulfide, a potential building block for pharmaceutically and agrochemically relevant products, is prepared and used for the first time in high-pressure-mediated 1,3-dipolar cycloaddition reactions with nitrones to synthesize (trifluoromethyl)sulfanyl isoxazolidines.
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