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Response to Savolitinib in a Patient with Advanced Poorly Differentiated Lung Carcinoma Positive for a Novel EML4-MET Gene Fusion.

Ganlu OuyangPei ShuYinyin XueFeng LuoYan Li
Published in: OncoTargets and therapy (2024)
This case uncovers a new type of MET fusion and expands the range of potential MET fusion targets in NSCLC. The patient responded to savolitinib, suggesting a reference basis for the treatment of similar cases with EML4-MET fusion in the future. Additional research is warranted to assess the biological significance of the EML4-MET fusion in NSCLC.
Keyphrases
  • tyrosine kinase
  • small cell lung cancer
  • case report
  • advanced non small cell lung cancer
  • dna methylation