The Association between Sex and Risk of Alzheimer's Disease in Adults with Down Syndrome.

Pooja Girish Mhatre Joseph H LeeDeborah PangWarren B ZigmanBenjamin TyckoSharon J Krinsky-McHale Yuchen YangWayne SilvermanNicole Schupf

Published in: Journal of clinical medicine (2021)

There is an age-associated effect of sex on the risk of AD, with men over 60 years old having six times the risk of AD compared with age-matched women, independent of APOE-ε4 status, ethnicity, and level of ID.

Keyphrases

cognitive decline
polycystic ovary syndrome
high fat diet
middle aged
mild cognitive impairment
pregnant women
insulin resistance