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Brain tumoroids: treatment prediction and drug development for brain tumors with fast, reproducible and easy-to-use personalized models.

Aurélie SoubéranCarine Jiguet-JiglaireSoline ToutainPhilippe MorandoNathalie Baeza-KalleeRomain AppayCéline BoucardThomas GraillonMikael MeyerKaissar FarahDominique Figarella-BrangerEmeline TabouretAurélie Tchoghandjian
Published in: Neuro-oncology (2024)
patient-derived tumoroid model that we developed offers a robust, user-friendly, low-cost and reproducible preclinical model valuable for therapeutic development of all type of primary or metastatic brain tumors, allowing their integration into forthcoming early-phase clinical trials.
Keyphrases
  • low cost
  • clinical trial
  • squamous cell carcinoma
  • white matter
  • stem cells
  • mesenchymal stem cells
  • multiple sclerosis
  • bone marrow
  • replacement therapy
  • phase iii