Development of Andrographolide-Carboxymethyl Chitosan Nanoparticles: Characterization, in vitro Release and in vivo Antimalarial Activity Study.

Retno Sari Aty WidyawaruyantiFranciscus B Tedy AninditaSinta Kusuma AstutiDwi Setyawan

Published in: Turkish journal of pharmaceutical sciences (2018)

The formation andrographolide-carboxymethyl chitosan nanoparticles affected the physical characte-ristics of andrographolide. The decrease crystallinity of andrographolide resulted in a lower melting point of andrographolide. Such changes provided a positive impact to the drug dissolution and then its activity.

Keyphrases

drug delivery
high resolution
mental health
wound healing
drug induced