Changes in laboratory value improvement and mortality rates over the course of the pandemic: an international retrospective cohort study of hospitalised patients infected with SARS-CoV-2.
Chuan HongHarrison G ZhangSehi L'YiGriffin M WeberPaul AvillachBryce W Q TanAlba Gutiérrez-SacristánClara-Lea BonzelNathan P PalmerAlberto MaloviniValentina TibolloYuan LuoMeghan R HutchMolei LiuFlorence BourgeoisRiccardo BellazziLuca ChiovatoFernando J Sanz VidorretaTrang T LeXuan WangWilliam YuanAntoine NeurazVincent BenoitBertrand MoalMichele MorrisDavid A HanauerSarah MaidlowKavishwar WagholikarShawn MurphyHossein EstiriAdeline MakoudjouPatric TippmannJeffery KlannRobert W FollettNils GehlenborgGilbert S OmennZongqi XiaArianna DagliatiShyam VisweswaranLav P PatelDanielle L MoweryEmily R SchriverMalarkodi Jebathilagam SamayamuthuRamakanth KavuluruSara Lozano-ZahoneroDaniela ZöllerAmelia L M TanByorn W L TanKee-Yuan NgiamJohn H HolmesPetra SchubertKelly ChoYuk-Lam HoBrett K Beaulieu-JonesMiguel Pedrera-JiménezNoelia García-BarrioPablo Serrano-BalazoteIsaac Kohanenull nullAndrew Michael SouthGabriel A BratT CaiPublished in: BMJ open (2022)
Admission profiles of patients hospitalised with SARS-CoV-2 infection did not differ greatly between the first and second waves of the pandemic, but there were notable differences in laboratory improvement rates during hospitalisation. Mortality risks among patients with similar risk profiles decreased over the course of the pandemic. The improvement in laboratory values and mortality risk was consistent across multiple countries.