Targeting cancer stem cells as a strategy for reducing chemotherapy resistance in head and neck cancers.
Dawid DornaJarosław PaluszczakPublished in: Journal of cancer research and clinical oncology (2023)
Evidence points to the advantage of combining classical chemotherapeutics with stemness modulators thanks to the joint targeting of the bulk of proliferating tumor cells and chemoresistant cancer stem cells, which could cause recurrence.