Characterization of binding, functional activity, and contractile responses of the selective 5-HT1F receptor agonist lasmiditan.

Eloisa Rubio-BeltránAlejandro Labastida-RamírezKristian Agmund HaanesAntoon van den BogaerdtAd J J C BogersEric ZanelliLaurent MeeusA H Jan DanserMichael R GralinskiPeter B SeneseKirk W JohnsonJoseph KovalchinCarlos M VillalónAntoinette MaassenVanDenBrink

Published in: British journal of pharmacology (2019)

Lasmiditan is a selective 5-HT1F receptor agonist devoid of vasoconstrictor activity. This may represent a cardiovascular safety advantage when compared to the triptans.

Keyphrases

transcription factor