BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study.

David B ZhenKari G RabeSteven GallingerSapna SyngalAnn G SchwartzMichael G GogginsRalph H HrubanMichele L CoteRobert R McWilliamsNicholas J RobertsLisa A Cannon-AlbrightDonghui LiLisa Anne Cannon-AlbrightRichard J WenstrupAnne-Renee HartmanDaniela SeminaraAlison P KleinGloria M Petersen

Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2014)

Genetic testing of multiple relevant genes in probands with a positive family history is warranted, particularly for familial pancreatic cancer.

Keyphrases

early onset
genome wide
breast cancer risk
gene expression
dna methylation
transcription factor