Association of per- and polyfluoroalkyl substances with the antioxidant bilirubin across pregnancy.

Kaitlin R TaiblAnne L DunlopM Ryan SmithDouglas I WalkerP Barry RyanParinya PanuwetElizabeth J CorwinKurunthachalam KannanDean P JonesCarmen J MarsitYouran TanDonghai LiangStephanie M EickDana Boyd Barr

Published in: Free radical biology & medicine (2024)

In a prospective cohort of pregnant African Americans, an increase in PFOA, PFHxS, and the PFAS mixture was associated with an increase in bilirubin. Our results suggest that, depending on pregnancy stage, prenatal PFAS exposure disrupts the maternal liver antioxidant capacity.

Keyphrases

pregnancy outcomes
pregnant women
preterm birth
oxidative stress
birth weight
drinking water
gestational age
weight loss