Mitochondrial Calcium uniporters are essential for meiotic progression in mouse oocytes by controlling Ca2+ entry.
Lu Yao ZhangMeng LinZhuan QingruiWang ZichuanLi JunjinLiu KexiongFu XiangweiYunpeng HouPublished in: Cell proliferation (2021)
These data provide new insight into the protective role that MCU-dependent mitochondrial Ca2+ signalling plays in meiotic progress, in addition to demonstrating a new mechanism of mitochondrial energy regulation by AMPK signalling that influences meiotic maturation.