Metabolic targets of watercress and PEITC in MCF-7 and MCF-10A cells explain differential sensitisation responses to ionising radiation.
Natasa S GiallourouIan R RowlandSteve D RothwellGraham PackhamDaniel M CommaneJonathan R SwannPublished in: European journal of nutrition (2018)
These findings support the potential prophylactic impact of watercress during radiotherapy. Extracted compounds from watercress and PEITC differentially modulate cellular metabolism collectively enhancing the therapeutic outcomes of radiotherapy.
Keyphrases
- breast cancer cells
- early stage
- radiation induced
- induced apoptosis
- locally advanced
- radiation therapy
- cell cycle arrest
- squamous cell carcinoma
- endoplasmic reticulum stress
- oxidative stress
- signaling pathway
- human health
- type diabetes
- metabolic syndrome
- pi k akt
- climate change
- risk assessment
- insulin resistance
- glycemic control