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Breed distributions for diabetes mellitus and hypothyroidism in Norwegian dogs.

N K RingstadF LingaasS I Thoresen
Published in: Canine medicine and genetics (2022)
These findings support that there are breeds more and less prone to develop DM and hypothyroidism. A strong genetic predisposition involved in the aetiology of these two diseases is therefore likely. Interestingly, there also appeared to be an inverse relationship of odds for the two diseases for some of the breeds since some breeds that had a high OR for DM or hypothyroidism had a lower OR for the other disease. This indicates that there may be different risk alleles/haplotypes for the two diseases. The possible aetiological relationship between canine DM and hypothyroidism should be further investigated.
Keyphrases
  • replacement therapy
  • genetic diversity
  • glycemic control
  • genome wide
  • dna methylation
  • smoking cessation
  • mass spectrometry
  • weight loss