Polygenic scores, diet quality, and type 2 diabetes risk: An observational study among 35,759 adults from 3 US cohorts.
Ruth J F LoosMarta Guasch-FerreA Heather EliassenWonil ChungYang HuBaoshan MaYanping LiJae Hee KangPeter KraftLiming LiangFrank B HuPaul W FranksJo Ann E MansonWalter Churchill WillettJose C FlorezFrank B HuPublished in: PLoS medicine (2022)
These data provide evidence for the independent associations of genetic risk and diet quality with incident type 2 diabetes and suggest that a healthy diet is associated with lower diabetes risk across all levels of genetic risk.