Standardized rice bran extract improves hepatic steatosis in HepG2 cells and ovariectomized rats.

Dong Wook Lim Hyejin Jeon Minji Kim Minseok Yoon Jonghoon Jung Sangoh Kwon Sueng-Mok Cho Min Young Um

Published in: Nutrition research and practice (2020)

RBS and γ-oryzanol effectively reduced lipid accumulation in a HepG2 cell hepatic steatosis model. RBS improves OVX-induced hepatic steatosis by regulating the SREBP1-mediated activation of lipogenic genes, suggesting the benefits of RBS in preventing fatty liver in postmenopausal women.

Keyphrases

postmenopausal women
bone mineral density
single cell
high glucose
diabetic rats
oxidative stress
stem cells
drug induced
gene expression
transcription factor
endothelial cells
dna methylation
bioinformatics analysis