Elafibranor and liraglutide improve differentially liver health and metabolism in a mouse model of non-alcoholic steatohepatitis.
Nikolaos PerakakisKonstantinos StefanakisMichael FeighSanne S VeidalChristos S MantzorosPublished in: Liver international : official journal of the International Association for the Study of the Liver (2021)
Liraglutide and elafibranor robustly but through different pathways improve overall metabolic health and liver status in NAFLD. These data indicate important differences in the respective mechanisms of action and support the notion for their evaluation as combination therapies in the future.