Hypermetabolism and impaired cerebrovascular reactivity beyond the standard MRI-identified tumor border indicate diffuse glioma extended tissue infiltration.
Martina SebökChristiaan Hendrik Bas van NiftrikGiovanni MuscasAthina PangaluKatharina SeystahlMichael WellerLuca RegliJorn FierstraPublished in: Neuro-oncology advances (2021)
We demonstrate hypermetabolism and impaired CVR beyond the standard MRI-defined tumor border, suggesting active tumor infiltration in the peritumoral environment.