Zn 2+ detection of a benzimidazole 8-aminoquinoline fluorescent sensor by inhibited tautomerization.
Harun TaşJörg AdamsJan C NamysloAndreas SchmidtPublished in: RSC advances (2021)
A new fluorescent chemosensor based on 8-aminoquinoline L1 bearing a benzimidazole moiety was synthesized, which exists as two predominant tautomers L1A and L1B in diluted DMSO-d 6 solution. Among various metal ions, L1 showed a highly selective and sensitive turn-on fluorescence response to the presence of Zn 2+ ions in methanol. The detection limit for Zn 2+ by L1 was calculated to be 1.76 × 10 -7 M. The 1 : 1 complexation ratio of the L1-Zn complex was confirmed through Job plot measurements. Complexation studies were performed by FT-IR, NMR and HR-ESI MS measurements and DFT calculations. With the gained insight, it was possible to successfully apply L1 in water sample analysis.
Keyphrases
- quantum dots
- heavy metals
- label free
- molecular docking
- living cells
- ms ms
- loop mediated isothermal amplification
- density functional theory
- sensitive detection
- mass spectrometry
- multiple sclerosis
- magnetic resonance
- real time pcr
- fluorescent probe
- single molecule
- molecular dynamics
- molecular dynamics simulations
- high resolution
- risk assessment
- solid state
- depressive symptoms
- case control
- carbon dioxide