A Highly Versatile X-ray and Electron Beam Diamond Dosimeter for Radiation Therapy and Protection.
Sara PettinatoMarco GirolamiAntonella StravatoValerio SerpenteDaniela MusioMaria C RossiDaniele Maria TrucchiRiccardo OlivieriStefano SalvatoriPublished in: Materials (Basel, Switzerland) (2023)
Radiotherapy is now recognized as a pillar in the fight against cancer. Two different types are currently used in clinical practice: (1) external beam radiotherapy, using high-energy X-rays or electron beams, both in the MeV-range, and (2) intraoperative radiotherapy, using low-energy X-rays (up to 50 keV) and MeV-range electron beams. Versatile detectors able to measure the radiation dose independently from the radiation nature and energy are therefore extremely appealing to medical physicists. In this work, a dosimeter based on a high-quality single-crystal synthetic diamond sample was designed, fabricated and characterized under low-energy X-rays, as well as under high-energy pulsed X-rays and electron beams, demonstrating excellent linearity with radiation dose and dose-rate. Detector sensitivity was measured to be 0.299 ± 0.002 µC/Gy under 6 MeV X-ray photons, and 0.298 ± 0.004 µC/Gy under 6 MeV electrons, highlighting that the response of the diamond dosimeter is independent of the radiation nature. Moreover, in the case of low-energy X-rays, an extremely low limit of detection (23 nGy/s) was evaluated, pointing out the suitability of the device to radiation protection dosimetry.
Keyphrases
- electron microscopy
- radiation therapy
- radiation induced
- locally advanced
- early stage
- clinical practice
- solar cells
- dual energy
- high resolution
- healthcare
- rectal cancer
- squamous cell carcinoma
- magnetic resonance imaging
- squamous cell
- mass spectrometry
- loop mediated isothermal amplification
- image quality
- magnetic resonance
- label free
- real time pcr
- quantum dots