Wash-free 3D imaging and detection of glioma with a novel neuropotential targeted AIE probe.
Junyong WuAnyao BiFan ZhengShuai HuangYongjiang LiJipeng DingDaxiong XiangWenbin ZengPublished in: Chemical communications (Cambridge, England) (2021)
We herein developed a novel tetraarylimidazole-based AIE probe TPIG-NP to selectively image and quantitatively detect glioma. Due to the distinct negatively charged glioma cells, TPIG-NP with an opposite charge could achieve wash-free imaging of glioma cells and 3D multicellular spheroids.