Daily Cannabis Use is Associated With Lower CNS Inflammation in People With HIV.

Caitlin Wei-Ming Watson Laura M CampbellNi Sun-SuslowSuzi HongAnya UmlaufRonald J EllisJennifer E IudicelloScott LetendreThomas D MarcotteRobert K HeatonErin E MorganIgor Grant

Published in: Journal of the International Neuropsychological Society : JINS (2021)

Current daily cannabis use was associated with lower levels of pro-inflammatory chemokines implicated in HIV pathogenesis and these chemokines were linked to the cognitive domain of learning which is commonly impaired in PWH. Cannabinoid-related reductions of MCP-1 and IP-10, if confirmed, suggest a role for medicinal cannabis in the mitigation of persistent inflammation and cognitive impacts of HIV.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
hiv testing
human immunodeficiency virus
hepatitis c virus
hiv aids
men who have sex with men
oxidative stress
physical activity
climate change
blood brain barrier