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MASTL inhibition promotes mitotic catastrophe through PP2A activation to inhibit cancer growth and radioresistance in breast cancer cells.

Yi Na YoonMin Ho ChoeKwan-Young JungSang-Gu HwangJeong Su OhJae Sung Kim
Published in: BMC cancer (2018)
Our data suggested that MASTL inhibition promoted mitotic catastrophe through PP2A activation, which led to the inhibition of cancer cell growth and a reversal of radioresistance in breast cancer cells.
Keyphrases
  • breast cancer cells
  • papillary thyroid
  • squamous cell
  • cell cycle
  • dna damage response
  • lymph node metastasis
  • childhood cancer
  • machine learning
  • cancer stem cells
  • big data
  • dna damage
  • cell proliferation
  • dna repair