Nickel-catalyzed enantioselective umpolung hydrogenation for stereoselective synthesis of β-amido esters.

Jianrong Steve ZhouSiyu GuoXiaohu ZhaoYonggui Robin Chi

Published in: Chemical communications (Cambridge, England) (2021)

Nickel complexes ligated by strongly donating diphosphines catalyze enantioselective hydrogenation for the preparation of acyclic and cyclic β-amido esters. A combination of acetic acid and indium powder provides protons and electrons to form nickel hydrido complexes under umpolung hydrogenation conditions.

Keyphrases

reduced graphene oxide
oxide nanoparticles
carbon nanotubes
metal organic framework
molecularly imprinted
mass spectrometry